MSM (12,000mg per scoop) MSM is a biologically active form of the mineral sulfur. Sulfur plays a particularly important role in tissue structure. MSM contributes to healthy joints because, as a form of sulfur, it adds to the benefits of glucosamine. It may aid glucosamine in its role to maintain healthy cartilage as well as helping to enhance joint flexibility and mobility. This supplement also relieves the pain of strained muscles and over extended joints, and can lessen inflammation and muscle spasms.